Optimization of liposomal topotecan for use in treating neuroblastoma
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چکیده
منابع مشابه
Optimization of liposomal topotecan for use in treating neuroblastoma
The purpose of this work was to develop an optimized liposomal formulation of topotecan for use in the treatment of patients with neuroblastoma. Drug exposure time studies were used to determine that topotecan (Hycamtin) exhibited great cytotoxic activity against SK-N-SH, IMR-32 and LAN-1 neuroblastoma human cell lines. Sphingomyelin (SM)/cholesterol (Chol) and 1,2-distearoyl-sn-glycero-3-phosp...
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Phase I study of combined pegylated liposomal doxorubicin with protracted daily topotecan for ovarian cancer.
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ژورنال
عنوان ژورنال: Cancer Medicine
سال: 2017
ISSN: 2045-7634
DOI: 10.1002/cam4.1083